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Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells

BACKGROUND: Our previous studies have confirmed that cobalt chloride (CoCl(2)) can induce the formation of polyploid giant cancer cells (PGCCs), which is the key to the heterogeneity of solid tumors. PGCC formation is closely related to the abnormal expression of cell cycle-related proteins and cell...

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Detalles Bibliográficos
Autores principales:	Liu, Kai, Zheng, Minying, Zhao, Qi, Zhang, Kexin, Li, Zugui, Fu, Fangmei, Zhang, Hao, Du, Jiaxing, Li, Yuwei, Zhang, Shiwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212590/ https://www.ncbi.nlm.nih.gov/pubmed/32393310 http://dx.doi.org/10.1186/s13046-020-01588-w

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