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Effects of deficiency in the RLBP1-encoded visual cycle protein CRALBP on visual dysfunction in humans and mice

Mutations in retinaldehyde-binding protein 1 (RLBP1), encoding the visual cycle protein cellular retinaldehyde-binding protein (CRALBP), cause an autosomal recessive form of retinal degeneration. By binding to 11-cis-retinoid, CRALBP augments the isomerase activity of retinoid isomerohydrolase RPE65...

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Detalles Bibliográficos
Autores principales:	Lima de Carvalho, Jose Ronaldo, Kim, Hye Jin, Ueda, Keiko, Zhao, Jin, Owji, Aaron P., Yang, Tingting, Tsang, Stephen H., Sparrow, Janet R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212638/ https://www.ncbi.nlm.nih.gov/pubmed/32188692 http://dx.doi.org/10.1074/jbc.RA120.012695

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