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Sampling time-dependent artifacts in single-cell genomics studies
Robust protocols and automation now enable large-scale single-cell RNA and ATAC sequencing experiments and their application on biobank and clinical cohorts. However, technical biases introduced during sample acquisition can hinder solid, reproducible results, and a systematic benchmarking is requir...
Autores principales: | Massoni-Badosa, Ramon, Iacono, Giovanni, Moutinho, Catia, Kulis, Marta, Palau, Núria, Marchese, Domenica, Rodríguez-Ubreva, Javier, Ballestar, Esteban, Rodriguez-Esteban, Gustavo, Marsal, Sara, Aymerich, Marta, Colomer, Dolors, Campo, Elias, Julià, Antonio, Martín-Subero, José Ignacio, Heyn, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212672/ https://www.ncbi.nlm.nih.gov/pubmed/32393363 http://dx.doi.org/10.1186/s13059-020-02032-0 |
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