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Construction of a pneumolysin deficient mutant in streptococcus pneumoniae serotype 1 strain 519/43 and phenotypic characterisation
Streptococcus pneumoniae capsular serotype 1 continues to pose a huge infectious disease burden in low- and middle-income countries, particularly in West Africa. However, studies on this important serotype have been hampered by the inability to genetically modify these strains. In this study we have...
Autores principales: | Terra, Vanessa S., Plumptre, Charles D., Wall, Emma C., Brown, Jeremy S., Wren, Brendan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212698/ https://www.ncbi.nlm.nih.gov/pubmed/31996316 http://dx.doi.org/10.1016/j.micpath.2020.103999 |
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