Cargando…

Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore

Background Fungal involvement of the paranasal sinuses has been described more than two centuries ago. In the current article, it is referred to as fungal rhinosinusitis (FRS) which is a general term that is used to describe a spectrum of pathologically, immunologically, and clinically different dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Alshaikh, Nada A, Alshiha, Khalid S, Yeak, Samuel, Lo, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212715/
https://www.ncbi.nlm.nih.gov/pubmed/32399321
http://dx.doi.org/10.7759/cureus.7587
_version_ 1783531663968436224
author Alshaikh, Nada A
Alshiha, Khalid S
Yeak, Samuel
Lo, Stephen
author_facet Alshaikh, Nada A
Alshiha, Khalid S
Yeak, Samuel
Lo, Stephen
author_sort Alshaikh, Nada A
collection PubMed
description Background Fungal involvement of the paranasal sinuses has been described more than two centuries ago. In the current article, it is referred to as fungal rhinosinusitis (FRS) which is a general term that is used to describe a spectrum of pathologically, immunologically, and clinically different disease entities affecting the paranasal sinuses where fungus is thought to be the major potential etiology. Objective To determine the incidence and spectrum of FRS in Singapore and to compare our findings with international figures through literature review. Methods A retrospective review of the clinical charts, radiological and laboratory results, and operative reports of all patients who underwent endoscopic sinus surgery at an ENT department of a tertiary referral hospital in Singapore over five-year period. Results Out of 533 functional endoscopic sinus surgeries performed during the period of the study for management of chronic rhinosinusitis, 44 (8.4%) were found to fit the criteria for diagnosis of FRS. Twenty (45.5%) were eosinophilic FRS and 24 (54.5%) were fungal balls. Invasive FRS has not been encountered. Clinical presentation, investigations, and management of both groups of patients are discussed. Conclusion Fungal rhinosinusitis is not uncommon in Singapore. Fungal ball and eosinophilic mucin fungal rhinosinusitis are among the most common forms encountered in this part of the world.
format Online
Article
Text
id pubmed-7212715
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-72127152020-05-12 Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore Alshaikh, Nada A Alshiha, Khalid S Yeak, Samuel Lo, Stephen Cureus Otolaryngology Background Fungal involvement of the paranasal sinuses has been described more than two centuries ago. In the current article, it is referred to as fungal rhinosinusitis (FRS) which is a general term that is used to describe a spectrum of pathologically, immunologically, and clinically different disease entities affecting the paranasal sinuses where fungus is thought to be the major potential etiology. Objective To determine the incidence and spectrum of FRS in Singapore and to compare our findings with international figures through literature review. Methods A retrospective review of the clinical charts, radiological and laboratory results, and operative reports of all patients who underwent endoscopic sinus surgery at an ENT department of a tertiary referral hospital in Singapore over five-year period. Results Out of 533 functional endoscopic sinus surgeries performed during the period of the study for management of chronic rhinosinusitis, 44 (8.4%) were found to fit the criteria for diagnosis of FRS. Twenty (45.5%) were eosinophilic FRS and 24 (54.5%) were fungal balls. Invasive FRS has not been encountered. Clinical presentation, investigations, and management of both groups of patients are discussed. Conclusion Fungal rhinosinusitis is not uncommon in Singapore. Fungal ball and eosinophilic mucin fungal rhinosinusitis are among the most common forms encountered in this part of the world. Cureus 2020-04-08 /pmc/articles/PMC7212715/ /pubmed/32399321 http://dx.doi.org/10.7759/cureus.7587 Text en Copyright © 2020, Alshaikh et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Otolaryngology
Alshaikh, Nada A
Alshiha, Khalid S
Yeak, Samuel
Lo, Stephen
Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title_full Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title_fullStr Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title_full_unstemmed Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title_short Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore
title_sort fungal rhinosinusitis: prevalence and spectrum in singapore
topic Otolaryngology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212715/
https://www.ncbi.nlm.nih.gov/pubmed/32399321
http://dx.doi.org/10.7759/cureus.7587
work_keys_str_mv AT alshaikhnadaa fungalrhinosinusitisprevalenceandspectruminsingapore
AT alshihakhalids fungalrhinosinusitisprevalenceandspectruminsingapore
AT yeaksamuel fungalrhinosinusitisprevalenceandspectruminsingapore
AT lostephen fungalrhinosinusitisprevalenceandspectruminsingapore