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ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino

The pervasive use of counterfeit sexual enhancement supplements is increasing worldwide. There are thousands of vendors on the internet while local gas stations and convenience stores are selling it across the United States (US). We report a case of right coronary artery ST-segment elevation and com...

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Autores principales: Deliwala, Smit, Haykal, Tarek, Dhillon, Harsukh, Shafi, Saadia, Bachuwa, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212751/
https://www.ncbi.nlm.nih.gov/pubmed/32399335
http://dx.doi.org/10.7759/cureus.7601
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author Deliwala, Smit
Haykal, Tarek
Dhillon, Harsukh
Shafi, Saadia
Bachuwa, Ghassan
author_facet Deliwala, Smit
Haykal, Tarek
Dhillon, Harsukh
Shafi, Saadia
Bachuwa, Ghassan
author_sort Deliwala, Smit
collection PubMed
description The pervasive use of counterfeit sexual enhancement supplements is increasing worldwide. There are thousands of vendors on the internet while local gas stations and convenience stores are selling it across the United States (US). We report a case of right coronary artery ST-segment elevation and complete heart block in a nitrate-free patient shortly after consuming three 950 mg pills of a sexual enhancer known as rhino and completing sexual intercourse. Coronary angiography revealed 100% occlusion of the right coronary artery and a drug-eluting stent was inserted with a transvenous pacer that he tolerated well, and recovered without complications. The counterfeit drug has gained traction for its high user satisfaction and low cost among recreational customers. The Food and Drug Administration (FDA), through its MedWatch program, has frequently released citations to consumers warning them against rhino since 2015, while their labs have recognized two prime ingredients: sildenafil and tadalafil. Although adverse cardiac risk with this therapeutic class is low, we aim to parse out its temporal relationship with rhino, an enhancer containing 14-200 times the prescription limits of sildenafil and tadalafil.
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spelling pubmed-72127512020-05-12 ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino Deliwala, Smit Haykal, Tarek Dhillon, Harsukh Shafi, Saadia Bachuwa, Ghassan Cureus Cardiology The pervasive use of counterfeit sexual enhancement supplements is increasing worldwide. There are thousands of vendors on the internet while local gas stations and convenience stores are selling it across the United States (US). We report a case of right coronary artery ST-segment elevation and complete heart block in a nitrate-free patient shortly after consuming three 950 mg pills of a sexual enhancer known as rhino and completing sexual intercourse. Coronary angiography revealed 100% occlusion of the right coronary artery and a drug-eluting stent was inserted with a transvenous pacer that he tolerated well, and recovered without complications. The counterfeit drug has gained traction for its high user satisfaction and low cost among recreational customers. The Food and Drug Administration (FDA), through its MedWatch program, has frequently released citations to consumers warning them against rhino since 2015, while their labs have recognized two prime ingredients: sildenafil and tadalafil. Although adverse cardiac risk with this therapeutic class is low, we aim to parse out its temporal relationship with rhino, an enhancer containing 14-200 times the prescription limits of sildenafil and tadalafil. Cureus 2020-04-09 /pmc/articles/PMC7212751/ /pubmed/32399335 http://dx.doi.org/10.7759/cureus.7601 Text en Copyright © 2020, Deliwala et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Deliwala, Smit
Haykal, Tarek
Dhillon, Harsukh
Shafi, Saadia
Bachuwa, Ghassan
ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title_full ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title_fullStr ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title_full_unstemmed ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title_short ST-elevation Myocardial Infarction and Complete Heart Block in a Nitrate-free Patient using a New Emerging Substance called Rhino
title_sort st-elevation myocardial infarction and complete heart block in a nitrate-free patient using a new emerging substance called rhino
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212751/
https://www.ncbi.nlm.nih.gov/pubmed/32399335
http://dx.doi.org/10.7759/cureus.7601
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