Cargando…

MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma

BACKGROUND: High-grade glioma (HGG) remains a recalcitrant clinical problem despite many decades of research. A major challenge in improving prognosis is the inability of current therapeutic strategies to address a clinically significant burden of infiltrating tumor cells that extend beyond the marg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brighi, Caterina, Reid, Lee, White, Alison L, Genovesi, Laura A, Kojic, Marija, Millar, Amanda, Bruce, Zara, Day, Bryan W, Rose, Stephen, Whittaker, Andrew K, Puttick, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212871/ https://www.ncbi.nlm.nih.gov/pubmed/32642689 http://dx.doi.org/10.1093/noajnl/vdaa030

Ejemplares similares

Comparative study of preclinical mouse models of high-grade glioma for nanomedicine research: the importance of reproducing blood-brain barrier heterogeneity
por: Brighi, Caterina, et al.
Publicado: (2020)

Relationship of In Vivo MR Parameters to Histopathological and Molecular Characteristics of Newly Diagnosed, Nonenhancing Lower-Grade Gliomas()
por: Luks, Tracy L., et al.
Publicado: (2018)

Radiomics MRI Phenotyping with Machine Learning to Predict the Grade of Lower-Grade Gliomas: A Study Focused on Nonenhancing Tumors
por: Park, Yae Won, et al.
Publicado: (2019)

Multicellular “hotspots” harbor high-grade potential in lower-grade gliomas
por: Kirby, Alastair J, et al.
Publicado: (2021)

High-throughput microRNA profiling of pediatric high-grade gliomas
por: Miele, Evelina, et al.
Publicado: (2014)

MR1 overexpression correlates with poor clinical prognosis in glioma patients
por: Kubica, Phillip, et al.
Publicado: (2021)

Establishment of patient-derived organoid models of lower-grade glioma
por: Abdullah, Kalil G, et al.
Publicado: (2021)

An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin
por: Zats, Liat Peretz, et al.
Publicado: (2022)

Parents’ experiences of postmortem tumor donation for high-grade gliomas: benefits and suggested improvements
por: Robertson, Eden G, et al.
Publicado: (2021)

Combined molecular subtyping, grading, and segmentation of glioma using multi-task deep learning
por: van der Voort, Sebastian R, et al.
Publicado: (2022)

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas
por: Zhang, Lei, et al.
Publicado: (2018)

Structural gray matter alterations in glioblastoma and high-grade glioma—A potential biomarker of survival
por: Lamichhane, Bidhan, et al.
Publicado: (2023)

Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay
por: Shuford, Stephen, et al.
Publicado: (2021)

Outcomes after combined use of intraoperative MRI and 5-aminolevulinic acid in high-grade glioma surgery
por: Schatlo, Bawarjan, et al.
Publicado: (2015)

The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress
por: Teng, Jian, et al.
Publicado: (2020)

Tumor mutational burden predicts survival in patients with low-grade gliomas expressing mutated IDH1
por: Alghamri, Mahmoud S, et al.
Publicado: (2020)

Transitioning to molecular diagnostics in pediatric high-grade glioma: experiences with the 2016 WHO classification of CNS tumors
por: Baugh, Joshua N, et al.
Publicado: (2021)

Simultaneous static and time-resolved nonenhanced peripheral MR angiography
por: Koktzoglou, Ioannis, et al.
Publicado: (2013)

Deep proteome investigation of high-grade gliomas reveals heterogeneity driving differential metabolism of 5-aminolevulinic acid
por: Ghantasala, Saicharan, et al.
Publicado: (2023)

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients
por: Izquierdo, Elisa, et al.
Publicado: (2021)

Immune deconvolution and temporal mapping identifies stromal targets and developmental intervals for abrogating murine low-grade optic glioma formation
por: de Andrade Costa, Amanda, et al.
Publicado: (2021)

Glycolytic expression in lower-grade glioma reveals an epigenetic association between IDH mutation status and PDL1/2 expression
por: Givechian, Kevin B, et al.
Publicado: (2020)

Pediatric high-grade gliomas and the WHO CNS Tumor Classification—Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates
por: Gielen, Gerrit H, et al.
Publicado: (2022)

Serial MR diffusion to predict treatment response in high-grade pediatric brain tumors: a comparison of regional and voxel-based diffusion change metrics
por: Rodriguez Gutierrez, Daniel, et al.
Publicado: (2013)

Early-onset grade 2-3 diffuse gliomas and schwannomas increase the risk of central nervous system tumors among the patients’ relatives
por: Alanen, Eljas, et al.
Publicado: (2023)

Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors
por: Kashani, Elham, et al.
Publicado: (2022)

MRI-guided focused ultrasound blood–brain barrier opening increases drug delivery and efficacy in a diffuse midline glioma mouse model
por: Martinez, Payton, et al.
Publicado: (2023)

Body-coil nonenhanced MR angiography using highly undersampled radial QISS
por: Edelman, Robert R, et al.
Publicado: (2013)

Diagnostic Performance of Arterial Spin Labeling for Grading Nonenhancing Astrocytic Tumors
por: Khashbat, Delgerdalai, et al.
Publicado: (2017)

An investigation of the conformity, feasibility, and expected clinical benefits of multiparametric MRI-guided dose painting radiotherapy in glioblastoma
por: Brighi, Caterina, et al.
Publicado: (2022)

Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma
por: Toedebusch, Ryan, et al.
Publicado: (2021)

Frequency of false-positive FISH 1p/19q codeletion in adult diffuse astrocytic gliomas
por: Ball, Matthew K, et al.
Publicado: (2020)

Long-lived tumor-associated macrophages in glioma
por: Georgieva, Petya B, et al.
Publicado: (2020)

Spatial concordance of DNA methylation classification in diffuse glioma
por: Verburg, Niels, et al.
Publicado: (2021)

Environmental and sex-specific molecular signatures of glioma causation
por: Claus, Elizabeth B, et al.
Publicado: (2021)

STAT3 is a biologically relevant therapeutic target in H3K27M-mutant diffuse midline glioma
por: Zhang, Liang, et al.
Publicado: (2022)

Receptor-driven invasion profiles in diffuse intrinsic pontine glioma
por: Karki, Anju, et al.
Publicado: (2021)

Distinct metabolic hallmarks of WHO classified adult glioma subtypes
por: Björkblom, Benny, et al.
Publicado: (2022)

Significance of molecular diagnostics for therapeutic decision-making in recurrent glioma
por: Blobner, Jens, et al.
Publicado: (2023)

Osteopontin regulates human glioma cell invasiveness and tumor growth in mice
por: Jan, Hsun-Jin, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_jskiq22iidrspej67ojeb3ulak