COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic

Potential pitfalls in the development, deployment and interpretation of antibody tests for COVID-19 are discussed. Lessons learned from the experience with the introduction of antibody tests for HIV are highlighted.Each test will need to be separately vetted for performance and clinical implementati...

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Detalles Bibliográficos
Autores principales: Weiss, Stanley H., Wormser, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212970/
https://www.ncbi.nlm.nih.gov/pubmed/32731192
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115078
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author Weiss, Stanley H.
Wormser, Gary P.
author_facet Weiss, Stanley H.
Wormser, Gary P.
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description Potential pitfalls in the development, deployment and interpretation of antibody tests for COVID-19 are discussed. Lessons learned from the experience with the introduction of antibody tests for HIV are highlighted.Each test will need to be separately vetted for performance and clinical implementation based upon rigorous clinical trial data. The issues we highlight will also be similarly important for vaccine and therapeutic drug efficacy trials.
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spelling pubmed-72129702020-05-11 COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic Weiss, Stanley H. Wormser, Gary P. Diagn Microbiol Infect Dis Article Potential pitfalls in the development, deployment and interpretation of antibody tests for COVID-19 are discussed. Lessons learned from the experience with the introduction of antibody tests for HIV are highlighted.Each test will need to be separately vetted for performance and clinical implementation based upon rigorous clinical trial data. The issues we highlight will also be similarly important for vaccine and therapeutic drug efficacy trials. Elsevier Inc. 2020-09 2020-05-11 /pmc/articles/PMC7212970/ /pubmed/32731192 http://dx.doi.org/10.1016/j.diagmicrobio.2020.115078 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Weiss, Stanley H.
Wormser, Gary P.
COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title_full COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title_fullStr COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title_full_unstemmed COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title_short COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic
title_sort covid-19: understanding the science of antibody testing and lessons from the hiv epidemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212970/
https://www.ncbi.nlm.nih.gov/pubmed/32731192
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115078
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