Cargando…

Schistosoma mansoni granulomas in the skeletal striated muscles in the murine model of neuroschistosomiasis: histological findings

Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy. No lesions have been reported in skeletal striated muscles due to schistos...

Descripción completa

Detalles Bibliográficos
Autores principales: Fidelis, Thiago Andre Alves, Brasileiro-Filho, Geraldo, Parreiras, Patricia M, Coelho, Paulo Marcos Z, Araujo, Neusa, Chaud, Marco Vinicius, Baldo, Denicezar Angelo, dos Santos, Nelson Brancaccio, Lambertucci, José Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212994/
https://www.ncbi.nlm.nih.gov/pubmed/32401896
http://dx.doi.org/10.1590/0074-02760190383
Descripción
Sumario:Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy. No lesions have been reported in skeletal striated muscles due to schistosomiasis mansoni in the literature. This short communication reports the histopathological findings on skeletal musculature in a murine model of neuroeschistosomiasis mansoni. Lesions were found in the tongue, masseter muscle, buccinator muscle, digastric muscle and temporalis muscle. Worm recovery was carried out to confirm the infection. We describe here, for the first time in the literature, injuries in the skeletal musculature due to Schistosoma mansoni nfection.