Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Current treatments for Pseudomonas aeruginosa infections are becoming less effective because of the increasing rates of multi-antibiotic resistance. Pharmacological targeting of virulence through inhibition of quorum sensing (QS) dependent virulence gene regulation has considerable therapeutic poten...

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Detalles Bibliográficos
Autores principales: Soukarieh, Fadi, Liu, Ruiling, Romero, Manuel, Roberston, Shaun N., Richardson, William, Lucanto, Simone, Oton, Eduard Vico, Qudus, Naim Ruhul, Mashabi, Alaa, Grossman, Scott, Ali, Sadiqur, Sou, Tomás, Kukavica-Ibrulj, Irena, Levesque, Roger C., Bergström, Christel A. S., Halliday, Nigel, Mistry, Shailesh N., Emsley, Jonas, Heeb, Stephan, Williams, Paul, Cámara, Miguel, Stocks, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213079/
https://www.ncbi.nlm.nih.gov/pubmed/32432073
http://dx.doi.org/10.3389/fchem.2020.00204

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