Cargando…
CBMS-04 SIGNIFICANT ROLE OF HYPOXIA IN THE EXPRESSION AND FUNCTION OF OSTEOPONTIN IN CD44-HIGHLY EXPRESSED GLIOMA STEM-LIKE CELLS IN TUMOR PROGRESSION OF GLIOBLASTOMA
The poor prognosis of glioblastoma multiforme (GBM) may be due to the surviving glioma stem-like cells (GSCs) in the tumor periphery after tumor resection. We demonstrated that CD44-expressed GSCs existed much more in the tumor periphery of high invasive (HI) type GBM than low invasive (LI) type GBM...
Autores principales: | Nishikawa, Masahiro, Inoue, Akihiro, Ohtsuka, Yoshihiro, Ozaki, Saya, Matsumoto, Shirabe, Suehiro, Satoshi, Yano, Hajime, Kanemura, Yonehiro, Tanaka, Junya, Ohnishi, Takanori, Kunieda, Takeharu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213098/ http://dx.doi.org/10.1093/noajnl/vdz039.024 |
Ejemplares similares
-
Hypoxia-induced phenotypic transition from highly invasive to less invasive tumors in glioma stem-like cells: Significance of CD44 and osteopontin as therapeutic targets in glioblastoma
por: Nishikawa, Masahiro, et al.
Publicado: (2021) -
CD44 expression in the tumor periphery predicts the responsiveness to bevacizumab in the treatment of recurrent glioblastoma
por: Nishikawa, Masahiro, et al.
Publicado: (2021) -
ML-04 PROGNOSTIC SIGNIFICANCE OF IMMUNOHISTOCHEMICAL SUBTYPES BASED ON THE STAGE OF B-CELL DIFFERENTIATION IN PRIMARY CNS LYMPHOMA
por: Inoue, Akihiro, et al.
Publicado: (2019) -
Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma
por: Nishikawa, Masahiro, et al.
Publicado: (2018) -
CBMS-01 Mechanism of brain tumor malignancy caused by aging and social isolation
por: Yamashita, Daisuke, et al.
Publicado: (2020)