MLTI-02. A PHASE I TRIAL OF SORAFENIB WITH WHOLE BRAIN RADIOTHERAPY (WBRT) IN BREAST CANCER PATIENTS WITH BRAIN METASTASES AND A CORRELATIVE FLT-PET BRAIN IMAGING STUDY IN PATIENTS RECEIVING WBRT +/- SORAFENIB

BACKGROUND: Sorafenib has demonstrated anti-tumor efficacy in breast cancer and radiosensitizing activity preclinically. [18F] 3’deoxy-3’-fluorothymidine (FLT) is a PET tracer which correlates with cellular proliferation and may improve response assessment. METHODS: A phase I trial of whole brain ra...

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Detalles Bibliográficos
Autores principales: Morikawa, Aki, Grkovski, Milan, Patil, Sujata, Jhaveri, Komal, Tang, Kendrick, Humm, John, Holodny, Andrei, Beal, Kathryn, Schoder, Heiko, Seidman, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213141/
http://dx.doi.org/10.1093/noajnl/vdz014.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213141/
http://dx.doi.org/10.1093/noajnl/vdz014.061

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