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BSCI-01. ACTIVATION OF c-Met/β1-INTEGRIN COMPLEX RESULTS IN INCREASE OF MESENCHYMAL GENE EXPRESSION AND STEM CELL POPULATION IN METASTATIC BREAST CANCER TO THE BRAIN AND SPINE
INTRODUCTION: C-met and β-integrins play a central role in nearly all stages of cancer metastasis. They bind at the cell surface, driving ligand independent co-activation of downstream pathways. Greater complex is seen in metastatic tumors vs. its primary tumor counterparts in patients. The molecula...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213224/ http://dx.doi.org/10.1093/noajnl/vdz014.000 |