Cargando…

MLTI-01. IMMUNOLOGICAL REPROGRAMMING IN THE CNS TUMOR MICROENVIRONMENT AND THERAPEUTIC EFFICACY OF RADIOTHERAPY WITH STAT3 BLOCKADE

BACKGROUND: Patients with central nervous system (CNS) tumors are typically treated with radiation therapy, but this is not curative and results in the upregulation of p-STAT3 that drives invasion, angiogenesis, and immune suppression. Therefore, we investigated the combined effect of an inhibitor o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ott, Martina, Hashimoto, Yuuri, Marisetty, Anantha, Wei, Jun, Zamler, Daniel, Leu, Jia-Shiun, Kong, Ling-Yuan, Zhou, Shouhao, Fuller, Gregory, de Groot, John, Priebe, Waldemar, Sulman, Erik, Heimberger, Amy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213227/ http://dx.doi.org/10.1093/noajnl/vdz014.060

Ejemplares similares

MiR-181 Family Modulates Osteopontin in Glioblastoma Multiforme
por: Marisetty, Anantha, et al.
Publicado: (2020)

LMD-20. Immune Suppressive Macrophages and Signal Transducer and Activator of Transcription 3 (STAT3) Expression are common in Melanoma Leptomeningeal Disease
por: Najem, Hinda, et al.
Publicado: (2021)

Ependymomas overexpress chemoresistance and DNA repair-related proteins
por: Ferguson, Sherise D., et al.
Publicado: (2017)

MLTI-10. ESTABLISHMENT OF A MULTIDISCIPLINARY BRAIN METASTASIS CLINIC TO FACILITATE PATIENT-CENTERED CARE AND COORDINATED RESEARCH
por: Li, Jing, et al.
Publicado: (2019)

MLTI-03. The relevance of the count of brain metastases for treatment and outcome in NSCLC
por: Reinecke, David, et al.
Publicado: (2021)

MLTI-04. The Role of the Outpatient Registered Nurse in the care of Brain Metastases
por: Hernandez, Juliana, et al.
Publicado: (2021)

MLTI-11. IMPLANTABLE POLYMERIC BCNU AS AN ADJUNCT TO SURGERY FOR METASTATIC INTRACRANIAL DISEASE
por: Ryken, Timothy, et al.
Publicado: (2019)

MLTI-19. VENOUS THROMBOEMBOLIC EVENTS IN PATIENTS WITH BRAIN METASTASES: THE PICOS SCORE
por: Wolpert, Fabian, et al.
Publicado: (2019)

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
por: Gabrusiewicz, Konrad, et al.
Publicado: (2018)

MLTI-09. UNDERWEIGHT AND WEIGHT LOSS ARE PREDICTORS OF POOR OUTCOME IN PATIENTS WITH BRAIN METASTASIS
por: Weller, Michael, et al.
Publicado: (2019)

MLTI-06. BEVACIZUMAB VERSUS SURGICAL INTERVENTION FOR RADIATION NECROSIS IN PREVIOUSLY IRRADIATED BRAIN METASTASES
por: Hong, Christopher, et al.
Publicado: (2019)

Rethinking medulloblastoma from a targeted therapeutics perspective
por: Hashimoto, Yuuri, et al.
Publicado: (2018)

MLTI-15. A CASE SERIES OF PRE-OPERATIVE GAMMA-KNIFE RADIOSURGERY FOR RESECTABLE BRAIN METASTASES
por: Takezaki, Tatsuya, et al.
Publicado: (2019)

MLTI-07. PREOPERATIVE VERSUS POSTOPERATIVE STEREOTACTIC RADIOSURGERY FOR LARGE BRAIN METASTASES: AN INTERNATIONAL META-ANALYSIS
por: Garcia, Henry Ruiz, et al.
Publicado: (2019)

MLTI-16. SYSTEMIC THERAPY FOLLOWING CRANIOTOMY IN PATIENTS WITH A SOLITARY BREAST CANCER BRAIN METASTASIS
por: Hulsbergen, Alexander, et al.
Publicado: (2019)

MLTI-05. Adjuvant re-irradiation improves local control of surgically resected recurrent brain metastases
por: Wilcox, Jessica, et al.
Publicado: (2021)

Ablative Radiotherapy Reprograms the Tumor Microenvironment of a Pancreatic Tumor in Favoring the Immune Checkpoint Blockade Therapy
por: Lee, Yu-Hung, et al.
Publicado: (2021)

Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system
por: Wei, Jun, et al.
Publicado: (2022)

Immune Microenvironment Landscape in CNS Tumors and Role in Responses to Immunotherapy
por: Najem, Hinda, et al.
Publicado: (2021)

MLTI-14. A SYSTEMATIC REVIEW OF TREATMENT PARADIGMS FOR PATIENTS WITH BREAST CANCER AND ONE OR MORE BRAIN METASTASES
por: Ellenbogen, Yosef, et al.
Publicado: (2019)

Hypoxia Potentiates Glioma-Mediated Immunosuppression
por: Wei, Jun, et al.
Publicado: (2011)

MLTI-17. DIFFERENTIATION OF RADIATION INJURY FROM RECURRENT BRAIN METASTASIS USING COMBINED FET PET/MRI RADIOMICS
por: Lohmann, Philipp, et al.
Publicado: (2019)

MLTI-08. AN EXCEPTIONAL INTRACRANIAL RESPONSE TO REPEAT RADIATION AND IMMUNOTHERAPY IN A PATIENT WITH METASTATIC, POORLY DIFFERENTIATED ADENOCARCINOMA OF THE LUNG
por: Sumrall, Ashley, et al.
Publicado: (2019)

MLTI-12. TIMING OF SYSTEMIC THERAPY ADMINISTRATION RELATIVE TO STEREOTACTIC RADIOSURGERY AND DEVELOPMENT OF RADIATION NECROSIS IN PATIENTS WITH BRAIN METASTASES
por: Hammoudeh, Lubna, et al.
Publicado: (2019)

Direct neuronal reprogramming of olfactory ensheathing cells for CNS repair
por: Sun, Xiu, et al.
Publicado: (2019)

Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis
por: Yasuoka, Yuuri, et al.
Publicado: (2020)

MLTI-06. Surgical resection plus stereotactic radiosurgery versus SRS alone for large brain metastases: a comparative study
por: Gutierrez, Enrique, et al.
Publicado: (2021)

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival
por: Lee, Ian, et al.
Publicado: (2012)

Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease
por: Li, He, et al.
Publicado: (2021)

Metabolic Reprogramming and Cell Adhesion in Acute Leukemia Adaptation to the CNS Niche
por: Sharma, Nitesh D., et al.
Publicado: (2021)

MLTI-05. IDENTIFYING BRAIN METASTATIC CASES FROM FREE TEXT CLINICAL NARRATIVES WITH REFINEMENT OF SEMANTIC HETEROGENEITY USING MACHINE LEARNING
por: Wells, Michael, et al.
Publicado: (2019)

Opening of the Blood–Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models
por: Sabbagh, Aria, et al.
Publicado: (2021)

Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma
por: Kassab, Cynthia, et al.
Publicado: (2019)

BSLD-01 DYNAMIC CONTROL OF CSF FOR PERSONALIZED CNS DRUG DELIVERY FOR LEPTOMINGEAL DISEASE
por: Kumthekar, Priya, et al.
Publicado: (2023)

MLTI-18. PRECISION IMAGING OF METASTATIC AND PRIMARY BRAIN TUMORS AFTER RADIATION WITH (18)F-FDOPA PET-MRI IS FEASIBLE AND COST EFFECT
por: Aboian, Mariam, et al.
Publicado: (2019)

MLTI-02. Impact of driver mutations on timing, pattern, treatment, and outcome in patients with brain metastases from non-small cell lung cancer
por: Jünger, Stephanie, et al.
Publicado: (2021)

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
por: Li, Zhilin, et al.
Publicado: (2020)

CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease
por: Najem, Hinda, et al.
Publicado: (2021)

MLTI-04. EVOLUTION OF TREATMENT PARADIGMS FOR PATIENTS WITH ≥1 BRAIN METASTASES FROM PRIMARY NON-SMALL-CELL LUNG CANCER – A SYSTEMATIC REVIEW
por: Brar, Karanbir, et al.
Publicado: (2019)

MLTI-03. FIRST-LINE STEREOTACTIC RADIOSURGERY COMBINED WITH SYSTEMIC TARGETED AND IMMUNE CHECKPOINT INHIBITOR THERAPY IN MELANOMA PATIENTS WITH NEWLY DIAGNOSED BRAIN METASTASES
por: Heumann, Thatcher, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_abmk9rptrdb2t0c1ne5vd6g38j