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Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age

BACKGROUND: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of congenital malformations, obstetric complications and neonatal morbidity. This study aims to investigate maternal, perinatal and neonatal outcomes of pregnancies in women with onset of T1DM le...

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Autores principales: Stone, Roy Gavin, Scully, Paul, Troy, Emma, Moloney, Yvonne, Quinn, Anne, Noctor, Eoin, Neylon, Orla, Slevin, John, Murphy, Annemarie, O'Gorman, Clodagh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213751/
https://www.ncbi.nlm.nih.gov/pubmed/32349996
http://dx.doi.org/10.1136/bmjdrc-2019-001080
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author Stone, Roy Gavin
Scully, Paul
Troy, Emma
Moloney, Yvonne
Quinn, Anne
Noctor, Eoin
Neylon, Orla
Slevin, John
Murphy, Annemarie
O'Gorman, Clodagh
author_facet Stone, Roy Gavin
Scully, Paul
Troy, Emma
Moloney, Yvonne
Quinn, Anne
Noctor, Eoin
Neylon, Orla
Slevin, John
Murphy, Annemarie
O'Gorman, Clodagh
author_sort Stone, Roy Gavin
collection PubMed
description BACKGROUND: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of congenital malformations, obstetric complications and neonatal morbidity. This study aims to investigate maternal, perinatal and neonatal outcomes of pregnancies in women with onset of T1DM less than 18 years of age. METHODS: This retrospective cohort study extracted data regarding prenatal, intrapartum and postnatal outcomes of pregnancies in women with onset of T1DM<18 years identified from the diabetes in pregnancy register at University Maternity Hospital Limerick, treated from July 1, 2007 to July 1, 2017. RESULTS: Seventeen women with onset of T1DM <18 years gave birth to 23 live infants during the period studied. 73.9% of pregnancies were unplanned. Only 21.7% of pregnancies took preconceptual folic acid. 60.9% of infants required treatment for hypoglycemia. CONCLUSION: The high prevalence of unplanned pregnancy and poor uptake of prepregnancy care must be improved on in order to improve outcomes for this high-risk group.
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spelling pubmed-72137512020-05-14 Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age Stone, Roy Gavin Scully, Paul Troy, Emma Moloney, Yvonne Quinn, Anne Noctor, Eoin Neylon, Orla Slevin, John Murphy, Annemarie O'Gorman, Clodagh BMJ Open Diabetes Res Care Clinical Care/Education/Nutrition BACKGROUND: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of congenital malformations, obstetric complications and neonatal morbidity. This study aims to investigate maternal, perinatal and neonatal outcomes of pregnancies in women with onset of T1DM less than 18 years of age. METHODS: This retrospective cohort study extracted data regarding prenatal, intrapartum and postnatal outcomes of pregnancies in women with onset of T1DM<18 years identified from the diabetes in pregnancy register at University Maternity Hospital Limerick, treated from July 1, 2007 to July 1, 2017. RESULTS: Seventeen women with onset of T1DM <18 years gave birth to 23 live infants during the period studied. 73.9% of pregnancies were unplanned. Only 21.7% of pregnancies took preconceptual folic acid. 60.9% of infants required treatment for hypoglycemia. CONCLUSION: The high prevalence of unplanned pregnancy and poor uptake of prepregnancy care must be improved on in order to improve outcomes for this high-risk group. BMJ Publishing Group 2020-04-28 /pmc/articles/PMC7213751/ /pubmed/32349996 http://dx.doi.org/10.1136/bmjdrc-2019-001080 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Clinical Care/Education/Nutrition
Stone, Roy Gavin
Scully, Paul
Troy, Emma
Moloney, Yvonne
Quinn, Anne
Noctor, Eoin
Neylon, Orla
Slevin, John
Murphy, Annemarie
O'Gorman, Clodagh
Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title_full Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title_fullStr Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title_full_unstemmed Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title_short Pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
title_sort pregnancy outcomes in women with onset of type 1 diabetes mellitus less than 18 years of age
topic Clinical Care/Education/Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213751/
https://www.ncbi.nlm.nih.gov/pubmed/32349996
http://dx.doi.org/10.1136/bmjdrc-2019-001080
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