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Idiopathic CD4+ T-cell Lymphocytopenia: Report of a Case 11 Years after Diagnosis

We report the case of a 23-year-old woman evaluated for asthenia and lymphocytopenia. Clinical examination was unremarkable but laboratory tests showed the presence of CD4 lymphocytopenia. Secondary causes of CD4 lymphocytopenia were ruled out and a previous diagnosis of idiopathic CD4+ T-cell lymph...

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Detalles Bibliográficos
Autores principales: Lorenzo Villalba, Noel, Zulfiqar, Abrar-Ahmad, Maouche, Yasmine, Cordoba Sosa, Zaida, Alonso Ortiz, Maria Belen, Andres, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213825/
https://www.ncbi.nlm.nih.gov/pubmed/32399448
http://dx.doi.org/10.12890/2020_001589
Descripción
Sumario:We report the case of a 23-year-old woman evaluated for asthenia and lymphocytopenia. Clinical examination was unremarkable but laboratory tests showed the presence of CD4 lymphocytopenia. Secondary causes of CD4 lymphocytopenia were ruled out and a previous diagnosis of idiopathic CD4+ T-cell lymphocytopenia was retained. CD4 lymphocytopenia has persisted for 11 years now but the patient has been clinically asymptomatic. LEARNING POINTS: CD4+ T-cell lymphocytopenia needs to be meticulously evaluated and secondary causes ruled out. The patient has been clinically asymptomatic for 11 years. Measurement of CD4 subsets twice yearly seems to be appropriate.