Cargando…
Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort
BACKGROUND: The biological underpinnings of the prognostic and predictive significance of a relative neutrophilia in patients with non-small lung cancer (NSCLC) are undefined. We sought to comprehensively examine the relationships between circulating and intratumoral neutrophil populations and featu...
Autores principales: | Mitchell, Kyle G, Diao, Lixia, Karpinets, Tatiana, Negrao, Marcelo V, Tran, Hai T, Parra, Edwin R, Corsini, Erin M, Reuben, Alexandre, Federico, Lorenzo, Bernatchez, Chantale, Dejima, Hitoshi, Francisco-Cruz, Alejandro, Wang, Jing, Antonoff, Mara B, Vaporciyan, Ara A, Swisher, Stephen G, Cascone, Tina, Wistuba, Ignacio I, Heymach, John V, Gibbons, Don L, Zhang, Jianjun, Haymaker, Cara L, Sepesi, Boris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213906/ https://www.ncbi.nlm.nih.gov/pubmed/32350118 http://dx.doi.org/10.1136/jitc-2019-000405 |
Ejemplares similares
-
Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response
por: Roelands, Jessica, et al.
Publicado: (2020) -
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
por: Negrao, Marcelo V, et al.
Publicado: (2021) -
Intratumoral injection reduces toxicity and antibody-mediated neutralization of immunocytokine in a mouse melanoma model
por: Baniel, Claire C, et al.
Publicado: (2020) -
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
por: Banchereau, Romain, et al.
Publicado: (2021) -
Intratumoral PPT1-positive macrophages determine immunosuppressive contexture and immunotherapy response in hepatocellular carcinoma
por: Weng, Jialei, et al.
Publicado: (2023)