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G4Killer web application: a tool to design G-quadruplex mutations
MOTIVATION: G-quadruplexes (G4) are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design of mutations leading to decreased propensity for G4 formation should be useful in studying G4 functions. Although tools exist for G4 prediction, no easily accessible t...
Autores principales: | Brazda, Vaclav, Kolomaznik, Jan, Mergny, Jean-Louis, Stastny, Jiri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214026/ https://www.ncbi.nlm.nih.gov/pubmed/31985802 http://dx.doi.org/10.1093/bioinformatics/btaa057 |
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