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Coolpup.py: versatile pile-up analysis of Hi-C data
MOTIVATION: Hi-C is currently the method of choice to investigate the global 3D organization of the genome. A major limitation of Hi-C is the sequencing depth required to robustly detect loops in the data. A popular approach used to mitigate this issue, even in single-cell Hi-C data, is genome-wide...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214034/ https://www.ncbi.nlm.nih.gov/pubmed/32003791 http://dx.doi.org/10.1093/bioinformatics/btaa073 |