Cargando…
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%−30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States. Together, SFTSV and HRTV are emerging segmented, negative-sense RNA viral (sNSV) pathogens with potential gl...
Autores principales: | Wang, Wenjie, Shin, Woo-Jin, Zhang, Bojie, Choi, Younho, Yoo, Ji-Seung, Zimmerman, Maxwell I., Frederick, Thomas E., Bowman, Gregory R., Gross, Michael L., Leung, Daisy W., Jung, Jae U., Amarasinghe, Gaya K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214099/ https://www.ncbi.nlm.nih.gov/pubmed/31914382 http://dx.doi.org/10.1016/j.celrep.2019.12.020 |
Ejemplares similares
-
Structure and function of the Toscana virus cap-snatching endonuclease
por: Jones, Rhian, et al.
Publicado: (2019) -
Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases
por: Reguera, Juan, et al.
Publicado: (2016) -
Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism
por: Kumar, Gyanendra, et al.
Publicado: (2021) -
The active form of the influenza cap-snatching endonuclease inhibitor baloxavir marboxil is a tight binding inhibitor
por: Todd, Brendan, et al.
Publicado: (2021) -
Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase Cap-Snatching Domains
por: Guilligay, Delphine, et al.
Publicado: (2014)