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SENP3 in monocytes/macrophages up‐regulates tissue factor and mediates lipopolysaccharide‐induced acute lung injury by enhancing JNK phosphorylation

The mechanisms underlying coagulation abnormalities in sepsis and septic acute lung injury remain unclear. Tissue factor (TF) initiates coagulation; its production can be regulated by reactive oxygen species (ROS); and monocytes/macrophages produce pathological TF during sepsis. The SUMO2/3 protease...

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Detalles Bibliográficos
Autores principales:	Chen, Xuelian, Lao, Yimin, Yi, Jing, Yang, Jie, He, Shuangjun, Chen, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214145/ https://www.ncbi.nlm.nih.gov/pubmed/32237051 http://dx.doi.org/10.1111/jcmm.15199

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