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Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it!
At the end of January 2020, a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments. From th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214318/ https://www.ncbi.nlm.nih.gov/pubmed/32434108 http://dx.doi.org/10.1016/j.ejca.2020.04.034 |
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author | Omarini, Claudia Maur, Michela Luppi, Gabriele Narni, Franco Luppi, Mario Dominici, Massimo Longo, Giuseppe Piacentini, Federico |
author_facet | Omarini, Claudia Maur, Michela Luppi, Gabriele Narni, Franco Luppi, Mario Dominici, Massimo Longo, Giuseppe Piacentini, Federico |
author_sort | Omarini, Claudia |
collection | PubMed |
description | At the end of January 2020, a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments. From the first Italian government restrictions (23rd February), Modena Cancer Center adopted practical health vigilance recommendations to minimise the risk of exposure to the virus without overlooking cancer management. From 23rd February to 31st March 2020, 1257 patients on active anticancer treatment for oncological or haematological malignancies attended our institution. All the staff activities were rescheduled following our practical coronavirus disease 2019 (COVID-19) guideline. During this period, we have tallied 9 cases of COVID-19 infection (0.71%) in patients with cancer and 3 cases (1.66%) in health workers. The mortality rate of our patients with cancer was 22%, consistent with the data reported in the literature. In conclusion, following our practical health vigilance recommendations, physicians should be confident in maintaining life-saving anticancer treatment without exceedingly increasing the risk of nosocomial COVID-19 infection. The high rate of mortality suggested that all patients on active anticancer treatment with flu-like symptoms have to be carefully screened for COVID-19 infection. |
format | Online Article Text |
id | pubmed-7214318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72143182020-05-12 Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! Omarini, Claudia Maur, Michela Luppi, Gabriele Narni, Franco Luppi, Mario Dominici, Massimo Longo, Giuseppe Piacentini, Federico Eur J Cancer Current Perspective At the end of January 2020, a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments. From the first Italian government restrictions (23rd February), Modena Cancer Center adopted practical health vigilance recommendations to minimise the risk of exposure to the virus without overlooking cancer management. From 23rd February to 31st March 2020, 1257 patients on active anticancer treatment for oncological or haematological malignancies attended our institution. All the staff activities were rescheduled following our practical coronavirus disease 2019 (COVID-19) guideline. During this period, we have tallied 9 cases of COVID-19 infection (0.71%) in patients with cancer and 3 cases (1.66%) in health workers. The mortality rate of our patients with cancer was 22%, consistent with the data reported in the literature. In conclusion, following our practical health vigilance recommendations, physicians should be confident in maintaining life-saving anticancer treatment without exceedingly increasing the risk of nosocomial COVID-19 infection. The high rate of mortality suggested that all patients on active anticancer treatment with flu-like symptoms have to be carefully screened for COVID-19 infection. Elsevier Ltd. 2020-07 2020-05-12 /pmc/articles/PMC7214318/ /pubmed/32434108 http://dx.doi.org/10.1016/j.ejca.2020.04.034 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Current Perspective Omarini, Claudia Maur, Michela Luppi, Gabriele Narni, Franco Luppi, Mario Dominici, Massimo Longo, Giuseppe Piacentini, Federico Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title_full | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title_fullStr | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title_full_unstemmed | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title_short | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! |
title_sort | cancer treatment during the coronavirus disease 2019 pandemic: do not postpone, do it! |
topic | Current Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214318/ https://www.ncbi.nlm.nih.gov/pubmed/32434108 http://dx.doi.org/10.1016/j.ejca.2020.04.034 |
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