A deubiquitylase with an unusually high-affinity ubiquitin-binding domain from the scrub typhus pathogen Orientia tsutsugamushi

Ubiquitin mediated signaling contributes critically to host cell defenses during pathogen infection. Many pathogens manipulate the ubiquitin system to evade these defenses. Here we characterize a likely effector protein bearing a deubiquitylase (DUB) domain from the obligate intracellular bacterium...

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Detalles Bibliográficos
Autores principales: Berk, Jason M., Lim, Christopher, Ronau, Judith A., Chaudhuri, Apala, Chen, Hongli, Beckmann, John F., Loria, J. Patrick, Xiong, Yong, Hochstrasser, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214410/
https://www.ncbi.nlm.nih.gov/pubmed/32393759
http://dx.doi.org/10.1038/s41467-020-15985-4

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