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Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease
Lipid-based RNA nanocarriers have been recently accepted as a novel therapeutic option in humans, thus increasing the therapeutic options for patients. Tailored nanomedicines will enable to treat chronic liver disease (CLD) and end-stage liver cancer, disorders with high mortality and few treatment...
Autores principales: | Woitok, Marius Maximilian, Zoubek, Miguel Eugenio, Doleschel, Dennis, Bartneck, Matthias, Mohamed, Mohamed Ramadan, Kießling, Fabian, Lederle, Wiltrud, Trautwein, Christian, Cubero, Francisco Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214425/ https://www.ncbi.nlm.nih.gov/pubmed/32393755 http://dx.doi.org/10.1038/s41419-020-2571-4 |
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