H7N9 influenza split vaccine with SWE oil-in-water adjuvant greatly enhances cross-reactive humoral immunity and protection against severe pneumonia in ferrets

Until universal influenza vaccines become available, pandemic preparedness should include developing classical vaccines against potential pandemic influenza subtypes. We here show that addition of SWE adjuvant, a squalene-in-water emulsion, to H7N9 split influenza vaccine clearly enhanced functional...

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Detalles Bibliográficos
Autores principales: de Jonge, Jørgen, van Dijken, Harry, de Heij, Femke, Spijkers, Sanne, Mouthaan, Justin, de Jong, Rineke, Roholl, Paul, Adami, Eduardo Alfredo, Akamatsu, Milena Apetito, Ho, Paulo Lee, Brunner, Livia, Collin, Nicolas, Friede, Martin, Ferreira, José A., Luytjes, Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214439/
https://www.ncbi.nlm.nih.gov/pubmed/32411401
http://dx.doi.org/10.1038/s41541-020-0187-4

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