Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

Colorectal cancer (CRC) is the fourth most common cancer type globally. Investigating the signaling pathways that maintain cancer cell phenotype can identify new biomarkers for targeted therapy. Aberrant transforming growth factor-β (TGFβ) signaling has been implicated in CRC progression, however, t...

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Detalles Bibliográficos
Autores principales: Elsafadi, Mona, Manikandan, Muthurangan, Almalki, Sami, Mahmood, Amer, Shinwari, Tasneem, Vishnubalaji, Radhakrishnan, Mobarak, Mohammad, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214449/
https://www.ncbi.nlm.nih.gov/pubmed/32393769
http://dx.doi.org/10.1038/s41419-020-2529-6

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