Cargando…

GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78

Lung adenocarcinoma remains a threat to human health due to its high rate of recurrence and distant metastasis. However, the molecular mechanism underlying lung adenocarcinoma metastasis remains yet incompletely understood. Here, we show that upregulated expression of polypeptide N-acetylgalactosami...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Jing, Liu, Wenwen, Wang, Jianzhen, Hao, Junxia, Wang, Yingyan, You, Xin, Du, Xiaohui, Zhou, Yang, Ben, Jing, Zhang, Xinri, Ye, Mingliang, Wang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214460/ https://www.ncbi.nlm.nih.gov/pubmed/32393740 http://dx.doi.org/10.1038/s41419-020-2537-6

Ejemplares similares

GRP78 in lung cancer
por: Xia, Shengkai, et al.
Publicado: (2021)

GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition
por: Lin, Jiaying, et al.
Publicado: (2017)

The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
por: Carlos, Anthony J., et al.
Publicado: (2021)

Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70
por: Li, Minjing, et al.
Publicado: (2009)

A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis
por: Yoo, Seung-Ah, et al.
Publicado: (2012)

The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment
por: Roller, Corinna, et al.
Publicado: (2013)

The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection
por: Ha, Dat P., et al.
Publicado: (2020)

Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium
por: Wang, Yong, et al.
Publicado: (2018)

Galectin-1 binds GRP78 to promote the proliferation and metastasis of gastric cancer
por: Zhang, Qi, et al.
Publicado: (2022)

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo
por: Park, Kyung-Won, et al.
Publicado: (2017)

Overexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells
por: Nami, Babak, et al.
Publicado: (2016)

Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014)

ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator
por: Liu, Ze, et al.
Publicado: (2023)

Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma
por: Zhao, Guohong, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress-Associated Chaperones, Bip/GRP78 and Calnexin are Overexpressed in Keratocystic Odontogenic Tumours
por: Pavli, Maria, et al.
Publicado: (2014)

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma
por: Abdel Malek, Mohamed A.Y., et al.
Publicado: (2014)

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells
por: Zhang, Xiang-Yang, et al.
Publicado: (2015)

Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation
por: Liu, Shin-Yun, et al.
Publicado: (2016)

Mitochondrial metabolic regulation by GRP78
por: Prasad, Manoj, et al.
Publicado: (2017)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells
por: Wang, Yingyan, et al.
Publicado: (2008)

The molecular chaperone BiP (GRP 78) inhibits the differentiation of normal human monocytes into immature dendritic cells
por: Vittecoq, O, et al.
Publicado: (2003)

GRP78 inhibits macrophage adhesion via SR-A
por: Bai, Hui, et al.
Publicado: (2014)

Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes
por: Tsurusawa, Naoko, et al.
Publicado: (2022)

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
por: Ibanez, Jorge, et al.
Publicado: (2023)

GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of α2M
por: Liu, Chang, et al.
Publicado: (2020)

Grp78 promotes the invasion of hepatocellular carcinoma
por: Su, Rongjian, et al.
Publicado: (2010)

GRP78 at the Centre of the Stage in Cancer and Neuroprotection
por: Casas, Caty
Publicado: (2017)

Targeting the GRP78 Pathway for Cancer Therapy
por: Lu, Guanhua, et al.
Publicado: (2020)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

Cadmium Induces the Expression of Grp78, an Endoplasmic Reticulum Molecular Chaperone, in LLC-PK1 Renal Epithelial Cells
por: Liu, Fang, et al.
Publicado: (2006)

Discovery of a Novel Target for the Dysglycemic Chromogranin A Fragment Pancreastatin: Interaction with the Chaperone GRP78 to Influence Metabolism
por: Biswas, Nilima, et al.
Publicado: (2014)

Expression and clinical significance of Glucose Regulated Proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus
por: Langer, Rupert, et al.
Publicado: (2008)

Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017)

Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells
por: Lu, Tong, et al.
Publicado: (2019)

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth
por: Ho, Kuen Yao, et al.
Publicado: (2013)

Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I
por: Thomas, Simmy, et al.
Publicado: (2013)

Endoplasmic reticulum chaperone BiP/GRP78 knockdown leads to autophagy and cell death of arginine vasopressin neurons in mice
por: Kawaguchi, Yohei, et al.
Publicado: (2020)

Identification of Glucose-Regulated Protein 78 (GRP78) as a Receptor in BHK-21 Cells for Duck Tembusu Virus Infection
por: Zhao, Dongmin, et al.
Publicado: (2018)

Data for peptide-binding assay with oriented immobilization of GRP78 in Biacore
por: Wang, Sheng-Hung, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ujft6h18pakeqaca755bsho36j