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SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression

SETDB1, a histone H3K9 methyltransferase, has been reported to be upregulated in a variety of tumors and promotes cancer development. However, the exact pathogenesis of SETDB1 in human colorectal cancer (CRC) is hitherto unknown. Here, we showed that SETDB1 expression was highly amplified in CRC. Fu...

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Detalles Bibliográficos
Autores principales:	Cao, Nan, Yu, Yali, Zhu, Hua, Chen, Meng, Chen, Ping, Zhuo, Mingxing, Mao, Yujuan, Li, Lianyun, Zhao, Qiu, Wu, Min, Ye, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214465/ https://www.ncbi.nlm.nih.gov/pubmed/32393761 http://dx.doi.org/10.1038/s41419-020-2561-6

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