Cargando…

Disc1 Carrier Mice Exhibit Alterations in Neural pIGF-1Rβ and Related Kinase Expression

Mutation of the disc1 gene underlies a broad range of developmental neuropsychiatric defects, including schizophrenia, depression, and bipolar disorder. The pathophysiological phenotypes linked with disc1 mutation are due to the truncation of the DISC1 primary protein structure. This leads to a defe...

Descripción completa

Detalles Bibliográficos
Autores principales: Sultana, Razia, Shrestha, Amita, Lee, Charles C., Ogundele, Olalekan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214624/
https://www.ncbi.nlm.nih.gov/pubmed/32431597
http://dx.doi.org/10.3389/fncel.2020.00094