Cargando…
Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits
Tendons are dense connective tissues, which are critical for the integrity and function of our musculoskeletal system. During tendon aging and degeneration, tendon stem/progenitor cells (TSPCs) experience profound phenotypic changes with declined cellular functions that can be linked to the known in...
Autores principales: | Yan, Zexing, Yin, Heyong, Brochhausen, Christoph, Pfeifer, Christian G., Alt, Volker, Docheva, Denitsa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214752/ https://www.ncbi.nlm.nih.gov/pubmed/32432103 http://dx.doi.org/10.3389/fbioe.2020.00406 |
Ejemplares similares
-
Boosting tendon repair: interplay of cells, growth factors and scaffold-free and gel-based carriers
por: Yan, Zexing, et al.
Publicado: (2018) -
Spectrum of Tendon Pathologies: Triggers, Trails and End-State
por: Steinmann, Sara, et al.
Publicado: (2020) -
In Vitro Comparison of 2D-Cell Culture and 3D-Cell Sheets of Scleraxis-Programmed Bone Marrow Derived Mesenchymal Stem Cells to Primary Tendon Stem/Progenitor Cells for Tendon Repair
por: Hsieh, Chi-Fen, et al.
Publicado: (2018) -
Rebuilding Tendons: A Concise Review on the Potential of Dermal Fibroblasts
por: Chu, Jin, et al.
Publicado: (2020) -
Understanding Tendons: Lessons from Transgenic Mouse Models
por: Delgado Caceres, Manuel, et al.
Publicado: (2018)