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FtH-Mediated ROS Dysregulation Promotes CXCL12/CXCR4 Axis Activation and EMT-Like Trans-Differentiation in Erythroleukemia K562 Cells
The cell-microenvironment communication is essential for homing of hematopoietic stem cells in stromal niches. Recent evidences support the involvement of epithelial-to-mesenchymal (EMT) process in hematopoietic stem cell homeostasis as well as in leukemia cells invasiveness and migration capability...
Autores principales: | Chirillo, Roberta, Aversa, Ilenia, Di Vito, Anna, Salatino, Alessandro, Battaglia, Anna Martina, Sacco, Alessandro, Di Sanzo, Maddalena Adriana, Faniello, Maria Concetta, Quaresima, Barbara, Palmieri, Camillo, Biamonte, Flavia, Costanzo, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214836/ https://www.ncbi.nlm.nih.gov/pubmed/32432042 http://dx.doi.org/10.3389/fonc.2020.00698 |
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