Cargando…
Bioinformatics and Biosimulations as Toolbox for Peptides and Peptidomimetics Design: Where Are We?
Peptides and peptidomimetics are strongly re-emerging as amenable candidates in the development of therapeutic strategies against a plethora of pathologies. In particular, these molecules are extremely suitable to treat diseases in which a major role is played by protein–protein interactions (PPIs)....
Autores principales: | D’Annessa, Ilda, Di Leva, Francesco Saverio, La Teana, Anna, Novellino, Ettore, Limongelli, Vittorio, Di Marino, Daniele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214840/ https://www.ncbi.nlm.nih.gov/pubmed/32432124 http://dx.doi.org/10.3389/fmolb.2020.00066 |
Ejemplares similares
-
Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca(2+) pumps: A computational study
por: Di Marino, Daniele, et al.
Publicado: (2015) -
Mechanistic insight into ligand binding to G-quadruplex DNA
por: Di Leva, Francesco Saverio, et al.
Publicado: (2014) -
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations
por: Chillemi, Giovanni, et al.
Publicado: (2008) -
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance
por: Losasso, Carmen, et al.
Publicado: (2008) -
Improving Small-Molecule Force Field Parameters in Ligand Binding Studies
por: Raniolo, Stefano, et al.
Publicado: (2021)