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The effect of ABCB1 polymorphism on sirolimus in renal transplant recipients: a meta-analysis

BACKGROUND: Sirolimus (SRL) is an immunosuppressive drug and substrate of the P-glycoprotein (P-GP) encoded by ABCB1. The relationship between ABCB1 polymorphism and the pharmacokinetics of SRL in different studies were conflicting in renal transplant recipients. Thus, this meta-analysis aims to inv...

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Detalles Bibliográficos
Autores principales: Shao, Shuai, Hu, Lei, Han, Zaigang, Hou, Kelu, Fang, Huihui, Zhang, Guijie, Feng, Yufei, Huang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215018/
https://www.ncbi.nlm.nih.gov/pubmed/32420174
http://dx.doi.org/10.21037/tau.2020.03.42