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COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis

OBJECTIVE: The objective of this study was to evaluate the pooled estimate of diabetes prevalence in young (<50 years) versus elderly (>50 years) COVID-19 cohorts. METHODS: Studies published between December-2019 and March-2020 reporting demographic and clinical characteristics of COVID-19 cas...

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Autores principales: Desai, Rupak, Singh, Sandeep, Parekh, Tarang, Sachdeva, Sonali, Sachdeva, Rajesh, Kumar, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Diabetes India. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215159/
https://www.ncbi.nlm.nih.gov/pubmed/32438333
http://dx.doi.org/10.1016/j.dsx.2020.05.021
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author Desai, Rupak
Singh, Sandeep
Parekh, Tarang
Sachdeva, Sonali
Sachdeva, Rajesh
Kumar, Gautam
author_facet Desai, Rupak
Singh, Sandeep
Parekh, Tarang
Sachdeva, Sonali
Sachdeva, Rajesh
Kumar, Gautam
author_sort Desai, Rupak
collection PubMed
description OBJECTIVE: The objective of this study was to evaluate the pooled estimate of diabetes prevalence in young (<50 years) versus elderly (>50 years) COVID-19 cohorts. METHODS: Studies published between December-2019 and March-2020 reporting demographic and clinical characteristics of COVID-19 cases were identified. A total of 11 studies included accounting for 2084 COVID-19 patients. RESULTS: The overall prevalence of diabetes in COVID-19 patients with a mean age>50 years was 13.2%, whereas studies with relatively younger patients (mean age <50 years) had a pooled prevalence of 9.0% CONCLUSION: The overall prevalence of diabetes in COVID-19 patients was found to be 13.2% with studies including relatively elderly patients showing higher rates of diabetes. The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment.
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spelling pubmed-72151592020-05-12 COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis Desai, Rupak Singh, Sandeep Parekh, Tarang Sachdeva, Sonali Sachdeva, Rajesh Kumar, Gautam Diabetes Metab Syndr Article OBJECTIVE: The objective of this study was to evaluate the pooled estimate of diabetes prevalence in young (<50 years) versus elderly (>50 years) COVID-19 cohorts. METHODS: Studies published between December-2019 and March-2020 reporting demographic and clinical characteristics of COVID-19 cases were identified. A total of 11 studies included accounting for 2084 COVID-19 patients. RESULTS: The overall prevalence of diabetes in COVID-19 patients with a mean age>50 years was 13.2%, whereas studies with relatively younger patients (mean age <50 years) had a pooled prevalence of 9.0% CONCLUSION: The overall prevalence of diabetes in COVID-19 patients was found to be 13.2% with studies including relatively elderly patients showing higher rates of diabetes. The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment. Diabetes India. Published by Elsevier Ltd. 2020 2020-05-12 /pmc/articles/PMC7215159/ /pubmed/32438333 http://dx.doi.org/10.1016/j.dsx.2020.05.021 Text en © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Desai, Rupak
Singh, Sandeep
Parekh, Tarang
Sachdeva, Sonali
Sachdeva, Rajesh
Kumar, Gautam
COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title_full COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title_fullStr COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title_full_unstemmed COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title_short COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis
title_sort covid-19 and diabetes mellitus: a need for prudence in elderly patients from a pooled analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215159/
https://www.ncbi.nlm.nih.gov/pubmed/32438333
http://dx.doi.org/10.1016/j.dsx.2020.05.021
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