Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives

Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a promising tool for the detection of viruses. Here, we review the development of microfluidic chips that could be used i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Jianjian, Yin, Juxin, Lv, Shaowu, Wang, Ben, Mu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215165/
https://www.ncbi.nlm.nih.gov/pubmed/32421630
http://dx.doi.org/10.1016/j.bios.2020.112291
_version_ 1783532122885062656
author Zhuang, Jianjian
Yin, Juxin
Lv, Shaowu
Wang, Ben
Mu, Ying
author_facet Zhuang, Jianjian
Yin, Juxin
Lv, Shaowu
Wang, Ben
Mu, Ying
author_sort Zhuang, Jianjian
collection PubMed
description Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a promising tool for the detection of viruses. Here, we review the development of microfluidic chips that could be used in response to viral detection, specifically for viruses involved in more recent outbreaks. The advantages as well as the disadvantages of microfluidic systems are discussed and analyzed. We also propose ideas for future development of these microfluidic chips and we expect this advanced technology to be used in the future for viral outbreaks.
format Online
Article
Text
id pubmed-7215165
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-72151652020-05-12 Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives Zhuang, Jianjian Yin, Juxin Lv, Shaowu Wang, Ben Mu, Ying Biosens Bioelectron Article Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a promising tool for the detection of viruses. Here, we review the development of microfluidic chips that could be used in response to viral detection, specifically for viruses involved in more recent outbreaks. The advantages as well as the disadvantages of microfluidic systems are discussed and analyzed. We also propose ideas for future development of these microfluidic chips and we expect this advanced technology to be used in the future for viral outbreaks. Elsevier B.V. 2020-09-01 2020-05-12 /pmc/articles/PMC7215165/ /pubmed/32421630 http://dx.doi.org/10.1016/j.bios.2020.112291 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhuang, Jianjian
Yin, Juxin
Lv, Shaowu
Wang, Ben
Mu, Ying
Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title_full Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title_fullStr Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title_full_unstemmed Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title_short Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
title_sort advanced “lab-on-a-chip” to detect viruses – current challenges and future perspectives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215165/
https://www.ncbi.nlm.nih.gov/pubmed/32421630
http://dx.doi.org/10.1016/j.bios.2020.112291
work_keys_str_mv AT zhuangjianjian advancedlabonachiptodetectvirusescurrentchallengesandfutureperspectives
AT yinjuxin advancedlabonachiptodetectvirusescurrentchallengesandfutureperspectives
AT lvshaowu advancedlabonachiptodetectvirusescurrentchallengesandfutureperspectives
AT wangben advancedlabonachiptodetectvirusescurrentchallengesandfutureperspectives
AT muying advancedlabonachiptodetectvirusescurrentchallengesandfutureperspectives

Ejemplares similares