Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in mice. However, it is unclear how changes in HSC glutamine metabolism contribute to...

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Detalles Bibliográficos
Autores principales: Du, Kuo, Chitneni, Satish K., Suzuki, Ayako, Wang, Ying, Henao, Ricardo, Hyun, Jeongeun, Premont, Richard T., Naggie, Susanna, Moylan, Cynthia A., Bashir, Mustafa R., Abdelmalek, Manal F., Diehl, Anna Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215180/
https://www.ncbi.nlm.nih.gov/pubmed/31881361
http://dx.doi.org/10.1016/j.jcmgh.2019.12.006

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