Cargando…

Whole Lotta Lipids—From HCV RNA Replication to the Mature Viral Particle

Replication of the hepatitis C virus (HCV) strongly relies on various lipid metabolic processes in different steps of the viral life cycle. In general, HCV changes the cells’ lipidomic profile by differentially regulating key pathways of lipid synthesis, remodeling, and utilization. In this review,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bley, Hanna, Schöbel, Anja, Herker, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215355/ https://www.ncbi.nlm.nih.gov/pubmed/32326151 http://dx.doi.org/10.3390/ijms21082888

Ejemplares similares

Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell–derived hepatocytes
por: Schöbel, Anja, et al.
Publicado: (2018)

Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells
por: Schöbel, Anja, et al.
Publicado: (2021)

Ultrastructural Features of Membranous Replication Organelles Induced by Positive-Stranded RNA Viruses
por: Nguyen-Dinh, Van, et al.
Publicado: (2021)

HCV Induces the Expression of Rubicon and UVRAG to Temporally Regulate the Maturation of Autophagosomes and Viral Replication
por: Wang, Linya, et al.
Publicado: (2015)

Fondazione Telethon and Unione Italiana Lotta alla Distrofia Muscolare, a successful partnership for neuromuscular healthcare research of value for patients
por: Ambrosini, Anna, et al.
Publicado: (2021)

Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein
por: Vogt, Dorothee A., et al.
Publicado: (2013)

HCV dsRNA-Activated Macrophages Inhibit HCV Replication in Hepatocytes
por: Wang, Yizhong, et al.
Publicado: (2015)

Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication
por: Bian, Wen-Xiu, et al.
Publicado: (2019)

Staufen1 promotes HCV replication by inhibiting protein kinase R and transporting viral RNA to the site of translation and replication in the cells
por: Dixit, Updesh, et al.
Publicado: (2016)

Secondary Structural Elements of the HCV X-region Involved in Viral Replication
por: Gupta, Nidhi, et al.
Publicado: (2015)

GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation
por: Kim, Jung-Hee, et al.
Publicado: (2017)

The Impact of Mevastatin on HCV Replication and Autophagy of Non-Transformed HCV Replicon Hepatocytes Is Influenced by the Extracellular Lipid Uptake
por: Vescovo, Tiziana, et al.
Publicado: (2019)

Viral killer toxins induce caspase-mediated apoptosis in yeast
por: Reiter, Jochen, et al.
Publicado: (2005)

Host cell mTORC1 is required for HCV RNA replication
por: Stöhr, Stefanie, et al.
Publicado: (2016)

Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection
por: Aydin, Yucel, et al.
Publicado: (2021)

The HCV Replicase Complex and Viral RNA Synthesis
por: Romero-Brey, Inés, et al.
Publicado: (2016)

Viral precursor polyproteins: keys of regulation from replication to maturation
por: Yost, Samantha A, et al.
Publicado: (2013)

Anti-HCV RNA Aptamers Targeting the Genomic cis-Acting Replication Element
por: Marton, Soledad, et al.
Publicado: (2011)

HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication
por: Wang, Linya, et al.
Publicado: (2017)

Visualization and Analysis of Hepatitis C Virus Structural Proteins at Lipid Droplets by Super-Resolution Microscopy
por: Eggert, Dennis, et al.
Publicado: (2014)

Consensus siRNA for inhibition of HCV genotype-4 replication
por: Zekri, Abdel Rahman N, et al.
Publicado: (2009)

Regulation of interferon signaling and HCV-RNA replication by extracellular matrix
por: Kuwashiro, Takuya, et al.
Publicado: (2018)

HCV replication in gastrointestinal mucosa: Potential extra-hepatic viral reservoir and possible role in HCV infection recurrence after liver transplantation
por: Russelli, Giovanna, et al.
Publicado: (2017)

Lipid Profiles and Hepatitis C Viral Markers in HCV-Infected Thalassemic Patients
por: Alavian, Seyed-Moayed, et al.
Publicado: (2011)

Protein Inhibitor of Activated STAT2 Restricts HCV Replication by Modulating Viral Proteins Degradation
por: Guo, Jing, et al.
Publicado: (2017)

Silencing HCV Replication in Its Reservoir
por: Youssef, Samar Samir, et al.
Publicado: (2018)

Autophagy in HCV Replication and Protein Trafficking
por: Chu, Ja Yeon Kim, et al.
Publicado: (2021)

The Role of the Liver-Specific microRNA, miRNA-122 in the HCV Replication Cycle
por: Kunden, Rasika D., et al.
Publicado: (2020)

Editorial: Significance of Cellular Lipids for Viral Replication and Pathogenesis
por: Desselberger, Ulrich, et al.
Publicado: (2022)

Adapted HCV JFH1 variant is capable of accommodating a large foreign gene insert and allows lower level HCV replication and viral production
por: Wang, Qi, et al.
Publicado: (2018)

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity
por: L'Hernault, Anne, et al.
Publicado: (2007)

Distribution of HCV genotypes and HCV RNA viral load in hepatitis infected patients of Kolar region, Karnataka, India
por: Kaur, Devinder, et al.
Publicado: (2022)

Lipid Metabolism and HCV Infection
por: Targett-Adams, Paul, et al.
Publicado: (2010)

Small molecule inhibitors of HCV replication from Pomegranate
por: Reddy, B. Uma, et al.
Publicado: (2014)

RNA Polymerase Activity and Specific RNA Structure Are Required for Efficient HCV Replication in Cultured Cells
por: Murayama, Asako, et al.
Publicado: (2010)

Substituted imidazopyridines as potent inhibitors of HCV replication()
por: Vliegen, Inge, et al.
Publicado: (2009)

Replication of Plus-Sense Viral RNA
Publicado: (2006)

Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly
por: Sun, Xiaoyu, et al.
Publicado: (2018)

Extracellular lipid-free apolipoprotein E inhibits HCV replication and induces ABCG1-dependent cholesterol efflux
por: Crouchet, Emilie, et al.
Publicado: (2017)

Inhibition of HCV Replication by Oxysterol-Binding Protein-Related Protein 4 (ORP4) through Interaction with HCV NS5B and Alteration of Lipid Droplet Formation
por: Park, In-Woo, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ln6rfud4m15me49oplkmdfbv1b