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Modified DNA Aptamers for C-Reactive Protein and Lactate Dehydrogenase-5 with Sub-Nanomolar Affinities

Human C-reactive protein (CRP) and lactate dehydrogenase are important markers in clinical laboratory testing—the former is used to detect in vivo inflammation, and the latter is used to detect cell necrosis and tissue destruction. We developed aptamers that bind to human CRP and human lactate dehyd...

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Detalles Bibliográficos
Autores principales: Minagawa, Hirotaka, Kataoka, Yuka, Fujita, Hiroto, Kuwahara, Masayasu, Horii, Katsunori, Shiratori, Ikuo, Waga, Iwao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215426/
https://www.ncbi.nlm.nih.gov/pubmed/32294882
http://dx.doi.org/10.3390/ijms21082683

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