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Winnie-APC(Min/+) Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation
(1) Background: Colorectal cancer (CRC) is among the best examples of the relationship between inflammation and increased cancer risk. (2) Methods: To examine the effects of spontaneous low-grade chronic inflammation on the pathogenesis of CRC, we developed a new murine model of colitis-associated c...
Autores principales: | De Santis, Stefania, Verna, Giulio, Serino, Grazia, Armentano, Raffaele, Cavalcanti, Elisabetta, Liso, Marina, Dicarlo, Manuela, Coletta, Sergio, Mastronardi, Mauro, Lippolis, Antonio, Tafaro, Angela, Santino, Angelo, Pinto, Aldo, Campiglia, Pietro, Huang, Alex Y., Cominelli, Fabio, Pizarro, Theresa T., Chieppa, Marcello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215554/ https://www.ncbi.nlm.nih.gov/pubmed/32340123 http://dx.doi.org/10.3390/ijms21082972 |
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