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Hypoxia, Inflammation and Necrosis as Determinants of Glioblastoma Cancer Stem Cells Progression

Tumor hypoxic microenvironment causes hypoxia inducible factor 1 alpha (HIF-1α) activation and necrosis with alarmins release. Importantly, HIF-1α also controls the expression of alarmin receptors in tumor cells that can bind to and be activated by alarmins. Human tumor tissues possess 1–2% of cance...

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Detalles Bibliográficos
Autores principales:	Papale, Marco, Buccarelli, Mariachiara, Mollinari, Cristiana, Russo, Matteo A., Pallini, Roberto, Ricci-Vitiani, Lucia, Tafani, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215563/ https://www.ncbi.nlm.nih.gov/pubmed/32290386 http://dx.doi.org/10.3390/ijms21082660

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