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Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 Downregulation

Due to a superior dose conformity to the target, proton beam therapy (PBT) continues to rise in popularity. Recently, considerable efforts have been directed toward discovering treatment options for use in combination with PBT. This study aimed to investigate the targeting of checkpoint kinase 1 (CH...

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Detalles Bibliográficos
Autores principales: Choi, Changhoon, Cho, Won Kyung, Park, Sohee, Shin, Sung-Won, Park, Won, Kim, Haeyoung, Choi, Doo Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215565/
https://www.ncbi.nlm.nih.gov/pubmed/32294924
http://dx.doi.org/10.3390/ijms21082691