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Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors

In our efforts to find new and selective thiazolidinone-based anti-Candida agents, we synthesized and tested 26 thiazolidinones against several Candida spp. and Gram-positive and Gram-negative bacteria. The compounds showed selective antifungal activity with potency similar to fluconazole and clotri...

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Detalles Bibliográficos
Autores principales: Güzel-Akdemir, Özlen, Carradori, Simone, Grande, Rossella, Demir-Yazıcı, Kübra, Angeli, Andrea, Supuran, Claudiu T., Akdemir, Atilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215574/
https://www.ncbi.nlm.nih.gov/pubmed/32331447
http://dx.doi.org/10.3390/ijms21082960