Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation

Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological processes of a wide spectrum of diseases. Recent studies showed their involvement in atrial fibrillation. They seem to become potential scre...

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Autores principales: Böhm, Allan, Vachalcova, Marianna, Snopek, Peter, Bacharova, Ljuba, Komarova, Dominika, Hatala, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215603/
https://www.ncbi.nlm.nih.gov/pubmed/32326592
http://dx.doi.org/10.3390/ijms21082742
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author Böhm, Allan
Vachalcova, Marianna
Snopek, Peter
Bacharova, Ljuba
Komarova, Dominika
Hatala, Robert
author_facet Böhm, Allan
Vachalcova, Marianna
Snopek, Peter
Bacharova, Ljuba
Komarova, Dominika
Hatala, Robert
author_sort Böhm, Allan
collection PubMed
description Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological processes of a wide spectrum of diseases. Recent studies showed their involvement in atrial fibrillation. They seem to become potential screening biomarkers for atrial fibrillation and even treatment targets for this arrhythmia. The aim of this review article was to summarize the latest knowledge about miRNA and their molecular relation to the pathophysiology, diagnosis and treatment of atrial fibrillation.
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spelling pubmed-72156032020-05-22 Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation Böhm, Allan Vachalcova, Marianna Snopek, Peter Bacharova, Ljuba Komarova, Dominika Hatala, Robert Int J Mol Sci Review Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological processes of a wide spectrum of diseases. Recent studies showed their involvement in atrial fibrillation. They seem to become potential screening biomarkers for atrial fibrillation and even treatment targets for this arrhythmia. The aim of this review article was to summarize the latest knowledge about miRNA and their molecular relation to the pathophysiology, diagnosis and treatment of atrial fibrillation. MDPI 2020-04-15 /pmc/articles/PMC7215603/ /pubmed/32326592 http://dx.doi.org/10.3390/ijms21082742 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Böhm, Allan
Vachalcova, Marianna
Snopek, Peter
Bacharova, Ljuba
Komarova, Dominika
Hatala, Robert
Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title_full Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title_fullStr Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title_full_unstemmed Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title_short Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation
title_sort molecular mechanisms, diagnostic aspects and therapeutic opportunities of micro ribonucleic acids in atrial fibrillation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215603/
https://www.ncbi.nlm.nih.gov/pubmed/32326592
http://dx.doi.org/10.3390/ijms21082742
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