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Defective Regulation of Membrane TNFα Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells

Besides an antigen-presenting function and ability to induce antitumor immune responses, dendritic cells (DCs) possess a direct tumoricidal activity. We previously reported that monocyte-derived IFNα-induced DCs (IFN-DCs) of glioblastoma multiforme patients express low levels of membrane TNFα molecu...

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Detalles Bibliográficos
Autores principales:	Tyrinova, Tamara, Leplina, Olga, Mishinov, Sergey, Tikhonova, Marina, Dolgova, Evgeniya, Proskurina, Anastasiya, Stupack, Vyacheslav, Bogachev, Sergey, Ostanin, Alexander, Chernykh, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215742/ https://www.ncbi.nlm.nih.gov/pubmed/32326230 http://dx.doi.org/10.3390/ijms21082898

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