Cargando…
A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites
Plant activators are chemicals that induce plant defense responses to various pathogens. Here, we reported a new potential plant activator, 6-(methoxymethyl)-2-[5-(trifluoromethyl)-2-pyridyl] pyrimidin-4-ol, named PPA2 (pyrimidin-type plant activator 2). Unlike the traditional commercial plant activ...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215783/ https://www.ncbi.nlm.nih.gov/pubmed/32295118 http://dx.doi.org/10.3390/ijms21082705 |
_version_ | 1783532267862228992 |
---|---|
author | Li, Jian Long, Ting Sun, Tie-Jun Lu, Yun Yin, Jian Yang, Yu-Bing Dai, Guang-Yi Zhu, Xiao-Yuan Yao, Nan |
author_facet | Li, Jian Long, Ting Sun, Tie-Jun Lu, Yun Yin, Jian Yang, Yu-Bing Dai, Guang-Yi Zhu, Xiao-Yuan Yao, Nan |
author_sort | Li, Jian |
collection | PubMed |
description | Plant activators are chemicals that induce plant defense responses to various pathogens. Here, we reported a new potential plant activator, 6-(methoxymethyl)-2-[5-(trifluoromethyl)-2-pyridyl] pyrimidin-4-ol, named PPA2 (pyrimidin-type plant activator 2). Unlike the traditional commercial plant activator benzothiadiazole S-methyl ester (BTH), PPA2 was fully soluble in water, and it did not inhibit plant growth or root system development in rice (Oryza sativa). PPA2 pretreatment significantly increased plant resistance against bacterial infection in both Arabidopsis and rice, in conjunction with increases in the level of jasmonoyl-isoleucine and 12-oxo-phytodienoic acid. In addition, metabolite profiling indicated that BTH significantly reduced the abundance of various primary metabolites in rice seedlings, including most amino acids, sugars, and organic acids; by contrast, PPA2 promoted their synthesis. Our results thus indicate that PPA2 enhances plant defenses against bacterial infection through the jasmonic acid pathway, and that as a water-soluble compound that can promote the synthesis of primary metabolites it has broad potential applications in agriculture. |
format | Online Article Text |
id | pubmed-7215783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72157832020-05-22 A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites Li, Jian Long, Ting Sun, Tie-Jun Lu, Yun Yin, Jian Yang, Yu-Bing Dai, Guang-Yi Zhu, Xiao-Yuan Yao, Nan Int J Mol Sci Article Plant activators are chemicals that induce plant defense responses to various pathogens. Here, we reported a new potential plant activator, 6-(methoxymethyl)-2-[5-(trifluoromethyl)-2-pyridyl] pyrimidin-4-ol, named PPA2 (pyrimidin-type plant activator 2). Unlike the traditional commercial plant activator benzothiadiazole S-methyl ester (BTH), PPA2 was fully soluble in water, and it did not inhibit plant growth or root system development in rice (Oryza sativa). PPA2 pretreatment significantly increased plant resistance against bacterial infection in both Arabidopsis and rice, in conjunction with increases in the level of jasmonoyl-isoleucine and 12-oxo-phytodienoic acid. In addition, metabolite profiling indicated that BTH significantly reduced the abundance of various primary metabolites in rice seedlings, including most amino acids, sugars, and organic acids; by contrast, PPA2 promoted their synthesis. Our results thus indicate that PPA2 enhances plant defenses against bacterial infection through the jasmonic acid pathway, and that as a water-soluble compound that can promote the synthesis of primary metabolites it has broad potential applications in agriculture. MDPI 2020-04-14 /pmc/articles/PMC7215783/ /pubmed/32295118 http://dx.doi.org/10.3390/ijms21082705 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Jian Long, Ting Sun, Tie-Jun Lu, Yun Yin, Jian Yang, Yu-Bing Dai, Guang-Yi Zhu, Xiao-Yuan Yao, Nan A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title | A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title_full | A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title_fullStr | A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title_full_unstemmed | A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title_short | A Pyrimidin-Like Plant Activator Stimulates Plant Disease Resistance and Promotes the Synthesis of Primary Metabolites |
title_sort | pyrimidin-like plant activator stimulates plant disease resistance and promotes the synthesis of primary metabolites |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215783/ https://www.ncbi.nlm.nih.gov/pubmed/32295118 http://dx.doi.org/10.3390/ijms21082705 |
work_keys_str_mv | AT lijian apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT longting apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT suntiejun apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT luyun apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yinjian apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yangyubing apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT daiguangyi apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT zhuxiaoyuan apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yaonan apyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT lijian pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT longting pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT suntiejun pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT luyun pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yinjian pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yangyubing pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT daiguangyi pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT zhuxiaoyuan pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites AT yaonan pyrimidinlikeplantactivatorstimulatesplantdiseaseresistanceandpromotesthesynthesisofprimarymetabolites |