In Vivo Analysis of Optic Fissure Fusion in Zebrafish: Pioneer Cells, Basal Lamina, Hyaloid Vessels, and How Fissure Fusion is Affected by BMP

Colobomata, persistent optic fissures, frequently cause congenital blindness. Here, we focused on optic fissure fusion using in vivo time-lapse imaging in zebrafish. We identified the fusion initiating cells, which we termed “pioneer cells.” Based on morphology, localization, and downregulation of t...

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Detalles Bibliográficos
Autores principales: Eckert, Priska, Knickmeyer, Max D., Heermann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215994/
https://www.ncbi.nlm.nih.gov/pubmed/32316164
http://dx.doi.org/10.3390/ijms21082760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215994/
https://www.ncbi.nlm.nih.gov/pubmed/32316164
http://dx.doi.org/10.3390/ijms21082760

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