Enhanced Cellular Uptake and Photodynamic Effect with Amphiphilic Fluorinated Porphyrins: The Role of Sulfoester Groups and the Nature of Reactive Oxygen Species

A class of amphiphilic photosensitizers for photodynamic therapy (PDT) was developed. Sulfonate esters of modified porphyrins bearing—F substituents in the ortho positions of the phenyl rings have adequate properties for PDT, including absorption in the red, increased cellular uptake, favorable intr...

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Detalles Bibliográficos
Autores principales: Pucelik, Barbara, Sułek, Adam, Drozd, Agnieszka, Stochel, Grażyna, Pereira, Mariette M., Pinto, Sara M. A., Arnaut, Luis G., Dąbrowski, Janusz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216003/
https://www.ncbi.nlm.nih.gov/pubmed/32316355
http://dx.doi.org/10.3390/ijms21082786

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