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A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization
Calmodulin (CaM) is a Ca(2+)-sensor that regulates a wide variety of target proteins, many of which interact through short basic helical motifs bearing two hydrophobic ‘anchor’ residues. CaM comprises two globular lobes, each containing a pair of EF-hand Ca(2+)-binding motifs that form a Ca(2+)-indu...
Autores principales: | Grant, Benjamin M. M., Enomoto, Masahiro, Ikura, Mitsuhiko, Marshall, Christopher B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216078/ https://www.ncbi.nlm.nih.gov/pubmed/32326637 http://dx.doi.org/10.3390/ijms21082751 |
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