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O(6)-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

The genome of living cells is continuously exposed to endogenous and exogenous attacks, and this is particularly amplified at high temperatures. Alkylating agents cause DNA damage, leading to mutations and cell death; for this reason, they also play a central role in chemotherapy treatments. A class...

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Detalles Bibliográficos
Autores principales:	Mattossovich, Rosanna, Merlo, Rosa, Miggiano, Riccardo, Valenti, Anna, Perugino, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216122/ https://www.ncbi.nlm.nih.gov/pubmed/32326075 http://dx.doi.org/10.3390/ijms21082878

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