Cargando…
MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies miRNA92a as a Regulator of the LRIG1 Stem Cell Gene
MicroRNAs (miRNAs) have a critical role in regulating stem cells (SCs) during development, and because aberrant expression of miRNAs occurs in various cancers, our goal was to determine if dysregulation of miRNAs is involved in the SC origin of colorectal cancer (CRC). We previously reported that al...
Autores principales: | Viswanathan, Vignesh, Opdenaker, Lynn, Modarai, Shirin, Fields, Jeremy Z., Gonye, Gregory, Boman, Bruce M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216254/ https://www.ncbi.nlm.nih.gov/pubmed/32316543 http://dx.doi.org/10.3390/ijms21082804 |
Ejemplares similares
-
Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells
por: Modarai, Shirin R., et al.
Publicado: (2016) -
The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells
por: Modarai, Shirin R., et al.
Publicado: (2018) -
The Proportion of ALDEFLUOR-Positive Cancer Stem Cells Changes with Cell Culture Density Due to the Expression of Different ALDH Isoforms
por: Opdenaker, Lynn M., et al.
Publicado: (2015) -
Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer
por: Stark, Victoria A., et al.
Publicado: (2023) -
APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development
por: Zhang, Tao, et al.
Publicado: (2020)