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MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies miRNA92a as a Regulator of the LRIG1 Stem Cell Gene

MicroRNAs (miRNAs) have a critical role in regulating stem cells (SCs) during development, and because aberrant expression of miRNAs occurs in various cancers, our goal was to determine if dysregulation of miRNAs is involved in the SC origin of colorectal cancer (CRC). We previously reported that al...

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Detalles Bibliográficos
Autores principales: Viswanathan, Vignesh, Opdenaker, Lynn, Modarai, Shirin, Fields, Jeremy Z., Gonye, Gregory, Boman, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216254/
https://www.ncbi.nlm.nih.gov/pubmed/32316543
http://dx.doi.org/10.3390/ijms21082804

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